Description

Glucosamine Sulphate & Chondroitin Sulphate Tablets

Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)

Exported by: Healthy Inc (Star Export House)

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a specialized Manufacturer of Glucosamine & Chondroitin Tablets in India. This synergistic combination is the global standard for Osteoarthritis Management and joint health. Unlike painkillers (NSAIDs) that only mask symptoms, these “Chondroprotective Agents” work to repair and maintain the actual structure of joint cartilage, slowing the progression of degenerative joint disease.

We offer Contract Manufacturing (Third Party) services for this high-demand therapeutic supplement. Glucosamine is highly hygroscopic (absorbs moisture from the air), which can cause tablets to become soft or discolored. Our WHO-GMP certified facility in Mumbai utilizes specialized low-humidity manufacturing zones (< 30% RH) and advanced Moisture-Barrier Film Coating to ensure the tablets remain stable and effective in all climates. Healthy Inc manages the export logistics, supplying orthopedic clinics, nutraceutical brands, and pharmacy chains across the USA, Europe, and Southeast Asia.

2. Product Specifications

3. Manufacturing Technology

Engineering a stable, swallowable tablet.

• The Manufacturer: Healthy Life Pharma Pvt. Ltd.

  • Hygroscopic Control: Glucosamine Sulphate is extremely sensitive to moisture. We manufacture in dehumidified suites and use specific binders (like PVP K-30) that work well in dry granulation processes to prevent degradation.

  • Shape Optimization: These active ingredients require high doses (often >1000mg total per dose). To make the tablet easy to swallow, we use high-density granulation to reduce volume and compress it into a streamlined Oval or Capsule-shaped tablet (Caplet).

  • Odor Masking: Chondroitin (derived from bovine or marine sources) can have a distinct smell. We use a flavored or vanilla-scented film coating to ensure patient acceptance.

• The Exporter: Healthy Inc

  • Regulatory Flexibility: Depending on the target country, we can file this product as a Dietary Supplement (FSSAI/Nutraceutical) or a Prescription Drug (CDSCO), providing the necessary dossiers for either pathway.

4. Quality Assurance

We adhere to strict Pharmacopoeial standards:

• Assay: We confirm the potency of both ingredients using HPLC to ensure 100% label claim.

• Disintegration: Despite being large tablets, we ensure they disintegrate within 30 minutes for maximum absorption.

• Microbiology: Since Chondroitin is of biological origin, we perform rigorous testing for pathogens (Salmonella, E. coli) to ensure absolute safety.

5. Why Use Glucosamine & Chondroitin?

The building blocks of healthy joints.

• Mechanism (Glucosamine): It is a precursor for Glycosaminoglycans (GAGs) and Proteoglycans, which are the main structural components of cartilage. It stimulates chondrocytes (cartilage cells) to produce new cartilage matrix and synovial fluid (joint oil).

• Mechanism (Chondroitin): It draws water into the cartilage, giving it elasticity and shock-absorbing properties. It also inhibits the enzymes (like elastase) that break down cartilage.

• Key Indications:

  • Osteoarthritis: Knee, hip, and spine arthritis.

  • Joint Stiffness: Improves range of motion and reduces morning stiffness.

  • Sports Recovery: Protects joints in athletes subject to high impact.

6. Export and Regulatory Support

We streamline the registration process for our B2B partners:

• Dossier Support: We offer CTD and ACTD Dossiers for quick registration.

• Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.

• Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).

7. Frequently Asked Questions

• Q: Who manufactures Glucosamine Chondroitin Tablets?

  A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.

• Q: Can I take it if I have a shellfish allergy?

  A: Consult a Doctor. Glucosamine is often derived from the shells of shrimp, crab, or lobster. While the allergen is usually in the meat, cross-contamination is possible. We can source Vegetarian (Corn-derived) Glucosamine upon special request for bulk orders.

• Q: Does it raise blood sugar?

  A: Generally No. While Glucosamine is a sugar derivative, studies show it does not significantly affect blood glucose or insulin sensitivity in Type 2 diabetics. However, monitoring is advised.

• Q: How long does it take to work?

  A: It is not a quick fix. It takes 4 to 8 weeks of consistent use to notice a significant reduction in pain and stiffness.

CLINICAL PHARMACOLOGY & SAFETY INFORMATION

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

• Standard Dose: 1500mg Glucosamine + 1200mg Chondroitin per day.

• Regimen: Usually taken as one tablet (500/400) three times daily OR one tablet (750/600) twice daily.

• Administration: Take with meals to reduce gastric upset.

9. Side Effects and Precautions

• Gastrointestinal: Nausea, heartburn, diarrhea, or constipation (mild).

• Warfarin Interaction: Warning: Glucosamine can increase the blood-thinning effect of Warfarin (Coumadin). INR monitoring is mandatory.

• Pregnancy: Safety not established. Generally avoided.

• Asthma: Rare reports of asthma exacerbation.

10. Storage Instructions

• Store below 25°C in a dry place.

• Keep bottle tightly closed. (Highly sensitive to humidity).