Description

Ciprofloxacin Tablets (250mg / 500mg / 750mg)

Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)

Exported by: Healthy Inc (Star Export House)

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a specialized Manufacturer of Ciprofloxacin Hydrochloride Tablets in India. Ciprofloxacin is a broad-spectrum Fluoroquinolone Antibiotic that revolutionized the treatment of severe bacterial infections. It is highly effective against Gram-negative bacteria (like E. coli, Salmonella, Pseudomonas) and select Gram-positive organisms. It remains the drug of choice for Urinary Tract Infections (UTIs), Typhoid Fever, and infectious diarrhea.

We offer Contract Manufacturing (Third Party) services for this high-volume antibiotic. Ciprofloxacin has an intensely bitter taste. Our WHO-GMP certified facility in Mumbai utilizes advanced Film Coating Technology to mask the taste completely, ensuring patient compliance. We also employ high-speed compression lines to meet the massive global demand for this essential medicine. Healthy Inc manages the export logistics, supplying government tenders, hospitals, and pharmacy chains across Africa, Latin America, and Southeast Asia.

2. Product Specifications

3. Manufacturing Technology

Potency against resistant bacteria.

• The Manufacturer: Healthy Life Pharma Pvt. Ltd.

  • Taste Masking: Ciprofloxacin is extremely bitter. We use a specialized HPMC-based Film Coating (Opadry) that provides a smooth, tasteless barrier, preventing the tablet from dissolving in the mouth and ensuring it is easy to swallow.

  • Dissolution Profile: To ensure rapid bacterial killing (concentration-dependent killing), our tablets are engineered to disintegrate rapidly, releasing >80% of the drug within 30 minutes in the stomach.

  • Hardness & Friability: We compress the tablets to a specific hardness that withstands shipping stress but does not delay disintegration.

• The Exporter: Healthy Inc

  • Tender Packs: We specialize in bulk packaging (1000s jars) and “Hospital Packs” (10×10 blisters) optimized for large-scale government health tenders.

4. Quality Assurance

We adhere to strict Pharmacopoeial standards:

• Assay: We confirm the potency is strictly within 90-110% of the label claim.

• Dissolution: Tested in 0.01N HCl to verify rapid release.

• Related Substances: We strictly monitor for degradation products (Fluoroquinolonic Acid) to ensure safety.

5. Why Use Ciprofloxacin?

The heavy hitter for tough infections.

• Mechanism: Ciprofloxacin inhibits two essential bacterial enzymes: DNA Gyrase and Topoisomerase IV. These enzymes are needed to uncoil and replicate bacterial DNA. By blocking them, Ciprofloxacin causes the bacterial DNA to break, leading to rapid cell death (Bactericidal).

• Key Indications:

  • Urinary Tract Infections (UTIs): Complicated and uncomplicated infections.

  • Typhoid Fever: Effective against Salmonella typhi.

  • Respiratory: Pneumonia (caused by Gram-negative bacteria) and Bronchitis.

  • Skin & Bone: Osteomyelitis and infected ulcers.

  • Gastrointestinal: Infectious diarrhea (Traveler’s Diarrhea, Cholera).

6. Export and Regulatory Support

We streamline the registration process for our B2B partners:

• Dossier Support: We offer CTD and ACTD Dossiers for quick registration.

• Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.

• Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).

7. Frequently Asked Questions

• Q: Who manufactures Ciprofloxacin Tablets?

  A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.

• Q: Is it Cipro?

  A: Cipro is the brand name (Bayer). We manufacture the Generic Equivalent (Ciprofloxacin HCl), which is bioequivalent.

• Q: Can I take it with milk?

  A: NO. Calcium (in milk/yogurt) binds to Ciprofloxacin and prevents its absorption. Take it 2 hours before or 6 hours after dairy products.

• Q: Is it safe for children?

  A: Generally No. It is usually avoided in children (<18 years) due to a theoretical risk of joint/cartilage damage, unless the infection is severe and no other drug works (e.g., Anthrax, Cystic Fibrosis).

CLINICAL PHARMACOLOGY & SAFETY INFORMATION

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

• UTI: 250mg to 500mg twice daily.

• Respiratory / Skin / Bone: 500mg to 750mg twice daily.

• Typhoid: 500mg twice daily for 7-10 days.

• Administration: Swallow whole with a full glass of water. Hydration is key to prevent crystalluria. Avoid taking with antacids, iron, or zinc supplements.

9. Side Effects and Precautions

• Tendonitis: Black Box Warning: Risk of tendon rupture (Achilles tendon), especially in elderly patients or those on steroids. Stop immediately if tendon pain occurs.

• CNS: Dizziness, confusion, hallucinations (rare).

• QT Prolongation: Can affect heart rhythm; caution in patients with heart conditions.

• Phototoxicity: Increased sensitivity to sunlight (sunburn risk).

• Neuropathy: Nerve damage (tingling/numbness) which can be permanent.

10. Storage Instructions

• Store below 25°C in a dry place.

• Protect from light.