Description

Chymotrypsin Tablets (100,000 AU)

Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)

Exported by: Healthy Inc (Star Export House)

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a specialized Manufacturer of Alpha Chymotrypsin Tablets in India. Chymotrypsin is a powerful Proteolytic Enzyme derived from bovine pancreas. It is widely prescribed as an Anti-inflammatory and Anti-edematous agent to accelerate the resolution of swelling, bruising, and hematomas following trauma, surgery, or dental procedures.

We offer Contract Manufacturing (Third Party) services for this specialized enzymatic formulation. Enzymes are proteins and are rapidly denatured (destroyed) by stomach acid. Our WHO-GMP certified facility in Mumbai utilizes advanced Enteric Coating Technology to ensure the tablet passes through the acidic stomach environment intact and releases the active enzyme only in the alkaline environment of the small intestine for absorption. Healthy Inc manages the export logistics, supplying orthopedic clinics, dental practices, and pharmacy chains across Southeast Asia, Africa, and the CIS region.

2. Product Specifications

3. Manufacturing Technology

Protecting the enzyme for maximum potency.

• The Manufacturer: Healthy Life Pharma Pvt. Ltd.

  • Enteric Protection: Chymotrypsin is useless if it dissolves in the stomach (pH 1-3). We apply a robust Methacrylic Acid Copolymer coating that resists gastric acid for over 2 hours, releasing the drug only when pH rises above 6.0 in the intestine.

  • Low-Heat Processing: Enzymes are heat-sensitive. We process granules at controlled low temperatures to prevent loss of enzymatic activity during drying and compression.

  • Potency Verification: Unlike standard chemical drugs, enzymes are measured by biological activity. We ensure every batch meets the strict “Armour Unit” activity requirements.

• The Exporter: Healthy Inc

  • Post-Surgical Packs: We specialize in packaging designed for short-term post-operative care (e.g., 5-day recovery packs) often requested by surgical centers.

4. Quality Assurance

We adhere to strict Pharmacopoeial standards:

• Enzymatic Activity: We assay the proteolytic power of the enzyme to ensure it can effectively break down peptide bonds.

• Dissolution: Tested in two stages:

  • Acid Stage: 0.1N HCl for 2 hours (Must remain intact).

  • Buffer Stage: pH 6.8 buffer (Must release enzyme).

• Microbial Limits: We strictly monitor for pathogens to ensure biological safety.

5. Why Use Chymotrypsin?

Speeds up the body’s natural cleanup crew.

• Mechanism: Chymotrypsin is a serine protease that cuts protein chains. When taken orally (and absorbed systemically), it breaks down Fibrin and other insoluble proteins trapped in inflamed tissues (exudates). By clearing this “debris” and improving micro-circulation, it allows fluid (edema) to drain faster and immune cells to reach the injury site more efficiently.

• Key Indications:

  • Post-Trauma: Reduces swelling and bruising from sprains, fractures, and sports injuries.

  • Post-Surgery: Speeds recovery after general surgery, liposuction, or orthopedic procedures.

  • Dentistry: Reduces swelling after tooth extraction or root canal treatment.

  • Pelvic Inflammatory Disease (PID): Used as an adjuvant to antibiotics to improve tissue penetration.

6. Export and Regulatory Support

We streamline the registration process for our B2B partners:

• Dossier Support: We offer CTD and ACTD Dossiers for quick registration.

• Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.

• Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).

7. Frequently Asked Questions

• Q: Who manufactures Chymotrypsin Tablets?

  A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.

• Q: Is it the same as Trypsin-Chymotrypsin?

  A: Similar. Trypsin-Chymotrypsin is a combination. Chymotrypsin Tablets contain only the Alpha Chymotrypsin enzyme, which is specifically potent against certain protein bonds. Both are used for inflammation.

• Q: When should I take it?

  A: Strictly on an EMPTY STOMACH. Take it 30-60 minutes before a meal. If taken with food, the enzyme will just digest your food instead of working on your inflammation.

• Q: Is it a painkiller?

  A: Not directly. It is not an analgesic like Ibuprofen. It reduces pain by reducing the pressure caused by swelling.

CLINICAL PHARMACOLOGY & SAFETY INFORMATION

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

• Adults: 1 to 2 tablets (100,000 AU) three times daily.

• Duration: Usually prescribed for 5 to 10 days until swelling subsides.

• Administration: Swallow whole. Do not chew or crush (destroying the coating will deactivate the enzyme and irritate the mouth). Must be taken on an empty stomach.

9. Side Effects and Precautions

• Gastrointestinal: Nausea, vomiting, diarrhea, gastric pain.

• Allergy: Rare allergic reactions (rash, itching) in patients sensitive to bovine proteins.

• Contraindications: Severe liver or kidney disease, blood clotting disorders (hemophilia), and generalized allergy to enzymes.

• Pregnancy: Safety not fully established; use only if clearly indicated.

10. Storage Instructions

• Store below 25°C in a dry, cool place.

• Protect from moisture. (Enzymes degrade rapidly in humidity).