Description

Chlorpheniramine Tablets (4mg)

Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)

Exported by: Healthy Inc (Star Export House)

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a specialized Manufacturer of Chlorpheniramine Maleate Tablets in India. Chlorpheniramine (often abbreviated as CPM) is a classic, highly effective First-Generation Antihistamine. It remains a household staple globally for the rapid relief of allergic symptoms such as runny nose, sneezing, itching, and watery eyes associated with hay fever and the common cold.

We offer Contract Manufacturing (Third Party) services for this high-volume OTC and prescription product. Chlorpheniramine is active at a low dose (4mg), which requires precision manufacturing to ensure content uniformity. Our WHO-GMP certified facility in Mumbai utilizes high-speed compression with automated weight control systems to produce millions of tablets with zero dose variation. Healthy Inc manages the export logistics, supplying pharmacies, supermarkets, and government health clinics across Africa, Southeast Asia, and the Caribbean.

2. Product Specifications

3. Manufacturing Technology

Small tablet, big relief.

• The Manufacturer: Healthy Life Pharma Pvt. Ltd.

  • Content Uniformity: A 4mg dose is very small relative to the tablet weight. We use Geometric Dilution blending techniques to ensure the active ingredient is perfectly distributed throughout the mix, preventing “hot spots” or sub-potent tablets.

  • Direct Compression: We utilize specialized direct compression excipients that ensure the tablet is hard enough to withstand shipping but disintegrates rapidly (< 15 mins) in the stomach for quick action.

  • Taste Masking: CPM has a bitter taste. While typically uncoated, we add sweeteners (like Saccharin or Aspartame) to the formulation to minimize the bitterness if the tablet touches the tongue before swallowing.

• The Exporter: Healthy Inc

  • Retail & Bulk: We offer versatile packaging, from 1000-count jars for dispensing doctors to 10-tablet blisters for OTC retail counters.

4. Quality Assurance

We adhere to strict Pharmacopoeial standards:

• Dissolution: We test release profiles to ensure >80% of the drug releases within 30 minutes.

• Assay: We confirm the potency is strictly within 90-110% of the label claim.

• Related Substances: We strictly monitor for degradation products to ensure stability over the 3-year shelf life.

5. Why Use Chlorpheniramine?

The reliable remedy for sneezes and sniffles.

• Mechanism: Chlorpheniramine is a potent H1 Receptor Antagonist. When your body encounters an allergen (pollen, dust, pet dander), it releases Histamine. Histamine binds to receptors causing itching, swelling, and fluid production (runny nose). Chlorpheniramine blocks these receptors, preventing the symptoms from starting.

• Key Indications:

  • Allergic Rhinitis (Hay Fever): Sneezing, runny nose, itchy throat.

  • Urticaria (Hives): Relieves itching and redness from skin allergies.

  • Common Cold: Dries up nasal secretions (anticholinergic effect) to stop a runny nose.

  • Insect Bites: Reduces local swelling and itch reaction.

6. Export and Regulatory Support

We streamline the registration process for our B2B partners:

• Dossier Support: We offer CTD and ACTD Dossiers for quick registration.

• Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.

• Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).

7. Frequently Asked Questions

• Q: Who manufactures Chlorpheniramine Tablets?

  A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.

• Q: Is it Piriton?

  A: Piriton is the brand name (GSK). We manufacture the Generic Equivalent (Chlorpheniramine Maleate), which works exactly the same.

• Q: Does it make you sleepy?

  A: Yes. Being a first-generation antihistamine, it crosses the blood-brain barrier and causes sedation. Do not drive or operate machinery.

• Q: Can I take it for a cold?

  A: Yes. It is very effective at drying up a runny nose, even if caused by a virus rather than an allergy.

CLINICAL PHARMACOLOGY & SAFETY INFORMATION

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

• Adults: 4mg every 4 to 6 hours. Max 24mg/day.

• Children (6-12 years): 2mg every 4 to 6 hours. Max 12mg/day.

• Children (2-6 years): 1mg every 4 to 6 hours.

• Administration: Swallow with water. Can be taken with or without food.

9. Side Effects and Precautions

• CNS: Drowsiness (very common), dizziness, disturbed coordination.

• Anticholinergic: Dry mouth, blurred vision, urinary retention, constipation.

• Contraindications: Glaucoma, Enlarged Prostate (BPH), and concurrent use of MAO Inhibitors.

• Elderly: Use with caution as they are more sensitive to confusion and hypotension side effects.

10. Storage Instructions

• Store below 25°C in a dry place.

• Protect from light.