Description

Thiamine, Riboflavin, Pyridoxine & Cyanocobalamine Tablets

(Neurotropic B-Complex)

Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified) Exported by: Healthy Inc (Star Export House)

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a specialized Manufacturer of Neurotropic B-Complex Tablets in India. This specific formulation focuses on the four essential B-vitamins critical for Nerve Health (Neuropathy) and Cellular Energy. Unlike broader multivitamins, this high-potency blend of B1, B2, B6, and B12 targets the nervous system’s repair mechanisms and prevents conditions like tingling, numbness, and burning sensations in the extremities.

We offer Contract Manufacturing (Third Party) services for this high-velocity product. B-Vitamins are notoriously unstable; Vitamin B1 smells sulfurous, while B2 and B12 degrade rapidly in light. Our WHO-GMP certified facility in Mumbai utilizes advanced Sugar Coating (Pan Coating) technology. This traditional yet effective method seals the tablet in a thick, sweet, and opaque shell, locking in the odor and blocking out UV light to ensure the vitamins remain potent for years. Healthy Inc manages the export logistics, supplying neurology clinics and pharmacy chains across Southeast Asia, the CIS region, and Latin America.

2. Product Specifications

3. Manufacturing Technology

Protecting the nerve builders.

• The Manufacturer: Healthy Life Pharma Pvt. Ltd.

  • Odor Barrier: Thiamine HCl has a strong, unpleasant “yeasty” or sulfur smell. We apply a Seal Coat (Shellac/Zein) followed by multiple layers of Sugar Syrup. This ensures the patient smells only the sweet coating, not the medicine inside.

  • Light Stability: Cyanocobalamin (B12) and Riboflavin (B2) lose potency if exposed to light. Our sugar coating includes opaque pigments (Titanium Dioxide and Iron Oxides) that act as a complete “Sunblock” for the tablet core.

  • Homogeneity: B12 is present in micrograms (mcg) while B1 is in milligrams (mg). We use Geometric Dilution blending techniques to ensuring the tiny amount of B12 is evenly distributed in every single tablet.

• The Exporter: Healthy Inc

  • Tropicalized Packaging: We use PVDC (Polyvinylidene Chloride) blister films instead of standard PVC. PVDC offers a high barrier against moisture, preventing the hygroscopic B-vitamins from absorbing water and turning the tablet soft or spotted in humid climates.

4. Quality Assurance

We adhere to strict Pharmacopoeial standards:

• Assay: We confirm the potency of all 4 vitamins using HPLC. We include calculated overages (extra API) during manufacturing to compensate for natural degradation, guaranteeing the product meets label claims at expiry.

• Dissolution: Despite the thick sugar coat, we test to ensure the tablet dissolves completely within 45 minutes in gastric fluid.

• Microbial Limits: Strict testing for pathogens to ensure safety.

5. Why Use This Combination?

The repair kit for your nerves.

• • Mechanism:

    • B1 (Thiamine): Essential for nerve energy. It helps the body produce ATP (fuel) for nerve cells.

* **B6 (Pyridoxine):** Crucial for the synthesis of neurotransmitters (chemical messengers) like serotonin and GABA.
* **B12 (Cyanocobalamin):** Required to build and maintain the **Myelin Sheath**—the protective insulation around nerves. Without it, nerves "short circuit" (neuropathy).
* **B2 (Riboflavin):** Works as an antioxidant, protecting nerve cells from oxidative stress.

• Key Indications:

  • Peripheral Neuropathy: Tingling/numbness in hands and feet (common in diabetics).

  • Neuritis: Inflammation of the nerves.

  • General Fatigue: Boosting cellular metabolism.

  • Mouth Ulcers: Preventing cracks at the corners of the mouth (Angular Stomatitis).

6. Export and Regulatory Support

• Dossier Support: CTD / ACTD available.

• Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.

• Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).

7. Frequently Asked Questions

• Q: Who manufactures these tablets? A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.

• Q: Why is my urine bright yellow? A: Vitamin B2 (Riboflavin). It is a natural fluorescent yellow pigment. The body flushes out what it doesn’t need. It is completely harmless.

• Q: Does it smell? A: The tablets are coated and sweet. However, the bottle may have a slight vitamin smell when first opened due to the B1. This is normal.

• Q: Is it Neurobion? A: Similar. Neurobion contains B1+B6+B12. Our formula adds B2 (Riboflavin) for extra skin and mucosal protection.

CLINICAL PHARMACOLOGY & SAFETY INFORMATION

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

• Therapeutic: 1 tablet three times daily.

• Prophylactic: 1 tablet daily.

• Administration: Swallow whole with water. Do not chew (the core tastes very bitter).

9. Side Effects and Precautions

• Gastrointestinal: Nausea, vomiting (rare).

• Urinary: Harmless yellow discoloration of urine.

• Interactions: Vitamin B6 reduces the effect of Levodopa (Parkinson’s medication). Alcohol decreases absorption of B1 and B12.

10. Storage Instructions

• Store below 25°C in a dry place.

• Keep away from light and moisture.