Amiodarone Tablet Manufacturer
Amiodarone is considered a high-risk medication due to its potential for serious side effects and interactions with other drugs. Here are some reasons why:
Toxicity: Amiodarone can cause toxicity in multiple organs, including the lungs, liver, and thyroid. For example, it can lead to pulmonary toxicity, such as interstitial pneumonitis or pulmonary fibrosis, and thyroid dysfunction, either hyperthyroidism or hypothyroidism.
Drug Interactions: It has many potential drug interactions because it affects liver enzymes that metabolize other medications. This can lead to increased or decreased levels of other drugs, potentially causing adverse effects or reducing their efficacy.
Long Half-Life: Amiodarone has a long half-life, which means it stays in the body for a long time. This prolonged presence can increase the risk of cumulative toxicity.
Side Effects: It can cause a variety of side effects, including skin discoloration, corneal deposits, and bradycardia (slow heart rate). Some side effects may not become apparent until long-term use.
Monitoring Requirements: Due to its potential for serious side effects, patients on amiodarone often require regular monitoring, including lung function tests, liver function tests, thyroid function tests, and eye exams.
Because of these factors, amiodarone is usually prescribed when the benefits outweigh the risks, and it is often used under close supervision by healthcare providers.
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