Description

Ibuprofen Tablets (200mg / 400mg / 600mg / 800mg)

Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)

Exported by: Healthy Inc (Star Export House)

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a specialized Manufacturer of Ibuprofen Tablets in India. Ibuprofen is one of the world’s most essential Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), widely used for its analgesic (pain-relieving), antipyretic (fever-reducing), and anti-inflammatory properties. It is the first-line treatment for headaches, dental pain, menstrual cramps, and arthritis.

We offer Contract Manufacturing (Third Party) services for this high-volume analgesic. Ibuprofen has a notoriously low melting point and can stick to punches during compression. Our WHO-GMP certified facility in Mumbai utilizes specialized “Anti-Sticking” tooling and advanced Film Coating technology to mask the drug’s characteristic burning taste and reduce gastric irritation. Healthy Inc manages the export logistics, supplying pharmacy chains, hospitals, and relief agencies across the USA, Europe, Africa, and Latin America.

2. Product Specifications

3. Manufacturing Technology

Overcoming the “Sticking” challenge.

• The Manufacturer: Healthy Life Pharma Pvt. Ltd.

  • Anti-Sticking Formulation: Ibuprofen has a low melting point (75°C) and tends to melt and stick under the heat of high-speed compression. We use specialized excipients (like Silicon Dioxide) and Chrome-Plated Tooling to ensure smooth, defect-free tablets even at high output speeds.

  • Taste Masking: Pure Ibuprofen causes a burning sensation in the throat. We apply a robust Polymer Film Coating (or traditional Sugar Coating) to completely mask the taste and facilitate easy swallowing.

     

  • Dissolution: We optimize the disintegration time to ensure the drug releases rapidly (< 30 mins) for quick pain relief.

• The Exporter: Healthy Inc

  • Range of Strengths: We manufacture the full spectrum: 200mg (OTC strength), 400mg (Extra Strength), and 600mg/800mg (Prescription Strength for arthritis).

4. Quality Assurance

We adhere to strict Pharmacopoeial standards:

• Dissolution: We test release profiles to ensure >80% of the drug releases within 60 minutes.

• Assay: We confirm the potency is strictly within 90-110% of the label claim.

• Impurity Profiling: We strictly monitor for degradation products (like 4-Isobutylacetophenone) to ensure safety.

5. Why Use Ibuprofen?

It blocks the pain signals at the source.

• Mechanism: Ibuprofen is a non-selective inhibitor of Cyclooxygenase (COX) enzymes. It blocks both COX-1 and COX-2, stopping the body from producing Prostaglandins. Prostaglandins are the chemicals that cause pain, inflammation, and fever. By reducing them, Ibuprofen effectively treats the symptoms.

• Key Indications:

  • Pain: Headache, toothache, back pain, muscle aches.

  • Inflammation: Rheumatoid Arthritis, Osteoarthritis, sports injuries.

  • Fever: Reduces high temperature in adults and children.

  • Dysmenorrhea: Relieves menstrual cramps.

6. Export and Regulatory Support

We streamline the registration process for our B2B partners:

• Dossier Support: We offer CTD and ACTD Dossiers for quick registration.

• Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.

• Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).

7. Frequently Asked Questions

• Q: Who manufactures Ibuprofen Tablets?

  A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.

• Q: Is it Advil or Motrin?

  A: Advil and Motrin are brand names. We manufacture the Generic Equivalent (Ibuprofen), which works exactly the same way.

• Q: Is it safe for the stomach?

  A: Take with Food. Like all NSAIDs, it can irritate the stomach lining and cause ulcers if taken empty. Always take it with milk or a meal.

• Q: Can I take it if I have high blood pressure?

  A: Consult a doctor. NSAIDs can raise blood pressure and strain the kidneys. Use with caution if you have hypertension.

CLINICAL PHARMACOLOGY & SAFETY INFORMATION

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

• Mild to Moderate Pain: 200mg to 400mg every 4-6 hours.

• Arthritis: 400mg to 800mg, 3-4 times daily (Max 3200mg/day).

• Administration: Swallow whole with a full glass of water. Do not lie down for 10 minutes after taking (to prevent esophageal irritation).

9. Side Effects and Precautions

• Gastrointestinal: Dyspepsia, nausea, ulcers, and bleeding (risk increases with dose and duration).

• Cardiovascular: Increased risk of heart attack or stroke with long-term high-dose use.

• Renal: Can cause acute kidney injury in dehydrated patients.

• Allergy: Contraindicated in patients with “Aspirin Asthma” (bronchospasm after taking aspirin).

10. Storage Instructions

• Store below 25°C in a dry place.

• Keep container tightly closed.