Description

Dried Aluminium Hydroxide & Magnesium Trisilicate Tablets

(Compound Magnesium Trisilicate Tablets BP)

Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)

Exported by: Healthy Inc (Star Export House)

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a specialized Manufacturer of Compound Magnesium Trisilicate Tablets in India. This is one of the most widely used, cost-effective Antacid Combinations in the world. It is the “Standard of Care” for the symptomatic relief of Peptic Ulcers, Hyperacidity, and Gastritis in public health systems and hospital tenders globally.

We offer Contract Manufacturing (Third Party) services for this high-volume essential medicine. The formulation relies on the classic synergy between Aluminium Hydroxide (slow-acting, potent neutralizer) and Magnesium Trisilicate (slow-acting, prolonged neutralizer with adsorbent properties). Our WHO-GMP certified facility in Mumbai is equipped with high-speed rotary presses capable of producing millions of these chewable tablets monthly, ensuring consistent hardness and rapid disintegration upon chewing. Healthy Inc manages the export logistics, supplying large-scale government tenders (CMS/MOH) across Africa, the Pacific Islands, and Southeast Asia.

2. Product Specifications

3. Manufacturing Technology

Reliable relief, scaleable production.

• The Manufacturer: Healthy Life Pharma Pvt. Ltd.

  • Granulation Mastery: Antacids are high-dose tablets (750mg of active ingredients). We use Wet Granulation with specific binders to compress this large volume of powder into a tablet that is not “rock hard” (so it doesn’t break teeth) but durable enough not to turn to dust during transport.

  • Bowel Balance: We strictly validate the ratio of Aluminium (Constipating) to Magnesium (Laxative) to ensuring the final formulation has a neutral effect on bowel motility, preventing the side effects common with single-ingredient antacids.

  • Grittiness Control: We use fine-mesh grades of Magnesium Trisilicate to minimize the “sandy” texture often associated with this generic, ensuring a smoother mouthfeel for the patient.

• The Exporter: Healthy Inc

  • Tender Specialist: This product is a staple for hospital tenders. We offer Bulk Packaging (1000s) and Eco-friendly Strip Packs specifically designed to meet the low-cost, high-volume requirements of government health ministries.

4. Quality Assurance

We adhere to strict Pharmacopoeial standards:

• Acid Neutralizing Capacity (ANC): This is the critical test. We verify that each tablet neutralizes the required milliequivalents (mEq) of Acid, ensuring it actually works to lower stomach acidity.

• Silica Content: For Magnesium Trisilicate, we test the ratio of Magnesium Oxide to Silicon Dioxide to ensure it meets the specific BP/USP monograph requirements for adsorbent activity.

• Heavy Metals: Strict testing for Arsenic and Lead, which can be naturally occurring impurities in mined minerals like magnesium silicates.

5. Why Use This Combination?

The slow and steady acid blocker.

• Mechanism:

  1. Aluminium Hydroxide: Reacts with stomach acid (HCl) to form Aluminium Chloride and water. It raises the pH slowly but effectively.

  2. Magnesium Trisilicate: Reacts with acid to form Magnesium Chloride and Colloidal Silica.

     • The Silica Gel Effect: The colloidal silica formed coats the stomach lining and the ulcer crater, acting as a physical protective barrier against further acid attack.

• Key Indications:

  • Peptic Ulcer Pain: Relief from the burning sensation.

  • Hyperacidity: Treatment of “Acid Stomach” and heartburn.

  • Gastritis: Inflammation of the stomach lining.

6. Export and Regulatory Support

• Dossier Support: CTD / ACTD available.

• Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.

• Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).

7. Frequently Asked Questions

• Q: Who manufactures these tablets?

  A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.

• Q: Is this the same as “Gelusil”?

  A: Similar. Gelusil is a brand that often uses this combination (sometimes adding Simethicone). This is the Generic Standard equivalent.

• Q: Why must I chew it?

  A: Surface Area. Chewing breaks the tablet into thousands of tiny particles. This huge surface area allows the minerals to neutralize the acid instantly. If swallowed whole, it works very slowly.

• Q: Does it interfere with antibiotics?

  A: Yes. Do not take it within 2 hours of taking Antibiotics (like Ciprofloxacin or Tetracycline) or Iron supplements. It binds to them and stops them from working.

CLINICAL PHARMACOLOGY & SAFETY INFORMATION

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

• Adults: 1 to 2 tablets chewed when required.

• Frequency: Can be taken up to 4 times a day (after meals and at bedtime).

• Administration: Chew thoroughly and follow with a glass of water.

9. Side Effects and Precautions

• Gastrointestinal: Generally well tolerated. High doses may cause mild diarrhea or constipation depending on the patient’s sensitivity.

• Renal: Contraindicated in severe kidney failure. Magnesium and Aluminium can accumulate to toxic levels in dialysis patients.

• Long Term Use: Prolonged use of Aluminium-containing antacids can lead to hypophosphatemia (low phosphate levels) in the blood.

10. Storage Instructions

• Store below 30°C in a dry place.

• Protect from moisture.