Description

Metoprolol Tartrate Tablets (25mg / 50mg / 100mg)

Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)

Exported by: Healthy Inc (Star Export House)

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a specialized Manufacturer of Metoprolol Tartrate Tablets in India. Metoprolol is a cardioselective Beta-1 Adrenergic Blocker used widely for the management of Hypertension, Angina Pectoris, and the acute treatment of Myocardial Infarction (Heart Attack). It works by relaxing blood vessels and slowing the heart rate to improve blood flow and lower blood pressure.

We offer Contract Manufacturing (Third Party) services for this high-volume cardiac drug. Metoprolol Tartrate is the Immediate Release form, requiring precise disintegration control to ensure rapid onset of action. Our WHO-GMP certified facility in Mumbai utilizes advanced compression and film-coating technologies to produce tablets that meet global dissolution standards. Healthy Inc manages the export logistics, supplying cardiology centers and pharmacy chains across the USA, Europe, and Southeast Asia.

2. Product Specifications

3. Manufacturing Technology

Precision in dosing and release is the standard.

• The Manufacturer: Healthy Life Pharma Pvt. Ltd.

  • Direct Compression / Wet Granulation: We utilize optimized granulation techniques to ensure excellent flow properties and compressibility, resulting in hard tablets that do not crumble during shipping but disintegrate rapidly (< 15 mins) in the patient’s stomach.

  • Content Uniformity: Metoprolol is a potent drug. We adhere to strict blend uniformity protocols to ensure every tablet contains exactly 25mg, 50mg, or 100mg, preventing dose variability.

  • Film Coating: We use a high-quality HPMC-based film coating to protect the tablet from moisture and make it easier to swallow.

• The Exporter: Healthy Inc

  • Global Compliance: We provide packaging that meets specific regional labeling requirements, including serialization for track-and-trace compliance in regulated markets.

4. Quality Assurance

We adhere to strict Pharmacopoeial standards:

• Dissolution: We test release profiles to ensure >80% of the drug releases within 30 minutes (Immediate Release standard).

• Assay: We confirm the potency is strictly within 90-110% of the label claim.

• Related Substances: We strictly monitor for impurities to ensure safety over the 3-year shelf life.

5. Why Use Metoprolol Tartrate?

It is the “Cardio-Protector” for the heart.

• Mechanism: It selectively blocks Beta-1 receptors located primarily in the heart. This reduces the effects of adrenaline (epinephrine), causing the heart to beat slower and with less force, which lowers blood pressure and reduces the heart’s demand for oxygen.

• Key Indications:

  • Hypertension: Lowers high blood pressure (often used with diuretics).

  • Angina Pectoris: Reduces the frequency of chest pain attacks.

  • Myocardial Infarction: Early treatment during a heart attack to reduce heart damage and death.

  • Arrhythmia: Controls uneven heartbeats.

6. Export and Regulatory Support

We streamline the registration process for our B2B partners:

• Dossier Support: We offer CTD and ACTD Dossiers for quick registration.

• Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.

• Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).

7. Frequently Asked Questions

• Q: Who manufactures Metoprolol Tablets?

  A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.

• Q: Is this the same as Toprol XL?

  A: NO. Toprol XL is Metoprolol Succinate (Extended Release). This product is Metoprolol Tartrate (Immediate Release, like Lopressor). They are not interchangeable without a doctor’s adjustment.

• Q: Does it cause fatigue?

  A: Yes. Feeling tired is a very common side effect because the drug slows down the heart rate.

• Q: Can I stop taking it suddenly?

  A: ABSOLUTELY NOT. Stopping a beta-blocker suddenly can cause a “rebound” heart attack or severe angina. You must taper off slowly under medical supervision.

CLINICAL PHARMACOLOGY & SAFETY INFORMATION

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

• Hypertension: 100mg to 450mg daily, in single or divided doses.

• Angina: 50mg to 100mg, two or three times daily.

• MI (Early Treatment): 50mg every 6 hours for 48 hours.

• Administration: Take with or immediately following meals (food increases absorption).

9. Side Effects and Precautions

• Bradycardia: Abnormally slow heart rate. Monitor pulse regularly.

• Bronchospasm: Use with caution in asthmatics (though it is cardioselective, high doses can block lung receptors).

• Hypotension: Dizziness due to low blood pressure.

• Masking Hypoglycemia: It can hide the symptoms of low blood sugar (like palpitations) in diabetics.

10. Storage Instructions

• Store below 25°C in a dry place.

• Protect from light and moisture.