Description
Paracetamol and Caffeine Tablets (500mg + 30mg / 500mg + 65mg)
Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)
Exported by: Healthy Inc (Star Export House)
1. Product Introduction
Healthy Life Pharma Pvt. Ltd. is a specialized Manufacturer of Paracetamol and Caffeine Tablets in India. This potent Analgesic Adjuvant Combination is specifically formulated for the relief of tough pain, particularly tension headaches and migraines. While Paracetamol acts as the primary painkiller, Caffeine acts as a “potentiator,” amplifying the analgesic effect by up to 40% compared to Paracetamol alone.
We offer Contract Manufacturing (Third Party) services for this high-demand formulation. Our WHO-GMP certified facility in Mumbai utilizes advanced granulation technology to ensure the uniform distribution of Caffeine Anhydrous within the tablet matrix. Healthy Inc manages the export logistics, supplying pharmacies, supermarkets, and distributors across Africa, the Middle East, and Southeast Asia.
2. Product Specifications
| Parameter | Specification |
| Product Name | Paracetamol and Caffeine Tablets |
| Generic Name | Paracetamol & Caffeine Tablets USP / BP / IP |
| CAS Number | 103-90-2 (Paracetamol) / 58-08-2 (Caffeine Anhydrous) |
| Strength | Standard: Paracetamol 500mg + Caffeine 30mg
Extra Strength: Paracetamol 500mg + Caffeine 65mg |
| Dosage Form | Film Coated Tablet / Caplet |
| Standard | USP / BP / IP Compliant |
| Therapeutic Class | Analgesic / Antipyretic / CNS Stimulant |
| Shelf Life | 36 Months |
| Packaging | 10×10 Blister / 10×12 Blister / Bulk Jar |
3. Manufacturing Technology
Enhancing pain relief through precise formulation.
The Manufacturer: Healthy Life Pharma Pvt. Ltd.
Uniformity: Caffeine is used in small quantities (30-65mg) compared to the bulk of Paracetamol (500mg). We use High-Shear Mixing to ensure the caffeine is perfectly distributed, preventing “hot spots” where a single tablet could cause jitters.
Taste Masking: Caffeine is intensely bitter. We apply a specialized Film Coating (Opadry) to mask the taste, making the tablet easy to swallow without the bitter aftertaste.
The Exporter: Healthy Inc
Stability: Caffeine Anhydrous is hygroscopic. We use moisture-resistant PVC/PVDC Blisters to prevent the tablet from softening or degrading in humid climates. We ensure compliance with caffeine regulations in destination countries (some regions regulate caffeine content in OTC medicines).
4. Quality Assurance
We adhere to strict Pharmacopoeial standards:
Assay: We simultaneously test for both ingredients using HPLC to confirm 100% label claim.
Dissolution: We verify that the Paracetamol releases rapidly to provide quick pain relief (usually within 15 minutes).
Related Substances: We monitor for 4-aminophenol (Paracetamol impurity) and specific Caffeine by-products.
5. Why Use Paracetamol + Caffeine?
It is the “Extra Strength” solution for headaches.
Mechanism:
Paracetamol: Blocks pain signals in the brain and reduces fever.
Caffeine: Constricts dilated blood vessels in the brain (vasoconstriction), which helps relieve migraine pain. It also increases the absorption rate of Paracetamol and sensitizes nerve receptors, making the painkiller work faster and stronger.
Key Indications:
Migraine & Headache: Especially effective for vascular headaches.
Fatigue-Associated Pain: Relief of body aches accompanied by tiredness.
Enhanced Relief: Used when plain Paracetamol is insufficient.
6. Export and Regulatory Support
We streamline the registration process for our B2B partners:
Dossier Support: We offer CTD and ACTD Dossiers for quick registration.
Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.
Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).
7. Frequently Asked Questions
Q: Who manufactures Paracetamol Caffeine Tablets?
A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.
Q: Is this the generic for Panadol Extra?
A: Yes, the 500mg/65mg strength is the generic equivalent of Panadol Extra.
Q: Can I drink coffee with this?
A: You should limit other caffeine sources (coffee, tea, cola) while taking this to avoid nervousness, insomnia, or rapid heartbeat.
CLINICAL PHARMACOLOGY & SAFETY INFORMATION
(For Registered Medical Practitioners & Patient Reference)
8. Dosage and Administration
Standard Dosage: 1 to 2 tablets every 4 to 6 hours as needed.
Maximum Dose: Do not exceed 8 tablets (4g Paracetamol) in 24 hours.
Administration: Can be taken on an empty stomach, but food may reduce the risk of caffeine-induced jitters.
9. Side Effects and Precautions
Caffeine Effects: Insomnia (sleeplessness), nervousness, irritability, and tachycardia (fast heart rate).
Gastric Irritation: Caffeine increases stomach acid; avoid in patients with severe acid reflux or ulcers.
Liver Warning: Contains Paracetamol. Overdose can cause liver failure.
10. Storage Instructions
Store below 25°C in a dry place.
Protect from light.
