Description
Ibuprofen and Paracetamol Tablets (400mg + 325mg)
Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)
Exported by: Healthy Inc (Star Export House)
1. Product Introduction
Healthy Life Pharma Pvt. Ltd. is a leading Manufacturer of Ibuprofen and Paracetamol Tablets in India. This potent Fixed-Dose Combination (FDC) combines the anti-inflammatory power of Ibuprofen with the analgesic and antipyretic properties of Paracetamol. It is widely recognized as one of the most effective non-opioid treatments for moderate to severe pain and fever.
We offer Contract Manufacturing (Third Party) services for this high-volume analgesic. Our WHO-GMP certified facility in Mumbai uses advanced Wet Granulation technology to ensure the stability of Ibuprofen (which has a low melting point) alongside Paracetamol. Healthy Inc manages the export logistics, ensuring consistent supply to pharmacies, hospitals, and distributors across Africa, Southeast Asia, and Latin America.
2. Product Specifications
| Parameter | Specification |
| Product Name | Ibuprofen and Paracetamol Tablets |
| Generic Name | Ibuprofen and Paracetamol Tablets USP / BP / IP |
| CAS Number | 15687-27-1 (Ibuprofen) / 103-90-2 (Paracetamol) |
| Strength | Ibuprofen 400mg + Paracetamol 325mg |
| Dosage Form | Film Coated Tablet / Caplet |
| Standard | USP / BP / IP Compliant |
| Therapeutic Class | NSAID / Analgesic / Antipyretic |
| Shelf Life | 36 Months |
| Packaging | 10×10 Blister / 10×15 Blister / Bulk Jar |
3. Manufacturing Ibuprofen + Paracetamol
Creating a stable, fast-acting painkiller requires precise formulation.
The Manufacturer: Healthy Life Pharma Pvt. Ltd.
Ibuprofen can be sticky and difficult to compress, while Paracetamol is brittle. We use specialized binders (like PVP K-30) and controlled temperature processing to create perfect granules. This ensures that the tablet remains hard enough to withstand shipping but disintegrates rapidly in the stomach for quick pain relief. We apply a Film Coating to mask the bitter taste and ensure ease of swallowing.
The Exporter: Healthy Inc
Healthy Inc ensures that the product reaches global markets in optimal condition. We use PVC/PVDC Blisters or Alu-Alu packs to protect the tablets from moisture, which can degrade the active ingredients. We handle all logistics, providing cost-effective shipping solutions for bulk orders.
4. Quality Assurance
We adhere to strict Pharmacopoeial standards:
Assay: We simultaneously test for Ibuprofen and Paracetamol content to ensure 100% label claim (400mg/325mg).
Dissolution: We verify that both drugs release at the correct rate to provide rapid onset of action.
Related Substances: We strictly monitor for impurities like 4-aminophenol and Ibuprofen degradation products to ensure safety.
5. Why Use Ibuprofen + Paracetamol?
It offers dual-action relief superior to monotherapy.
Mechanism:
Ibuprofen: Blocks COX enzymes to reduce inflammation and pain at the site of injury.
Paracetamol: Acts centrally in the brain to block pain signals and reduce fever.
Synergy: Together, they provide stronger pain relief than either drug taken alone.
Key Indications:
Musculoskeletal Pain: Back pain, arthritis, and muscle strains.
Dental Pain: Severe toothache and post-extraction pain.
Post-Operative Pain: Management of pain after minor surgeries.
Fever: Reduction of high fever unresponsive to Paracetamol alone.
6. Export and Regulatory Support
We streamline the registration process for our B2B partners:
Dossier Support: We offer CTD and ACTD Dossiers for quick registration.
Certificates: Free Sale Certificate (FSC), COPP (WHO-GMP), and COA.
Logistics: Efficient shipping via Air or Sea (FOB Mumbai / CIF).
7. Frequently Asked Questions
Q: Who manufactures Ibuprofen Paracetamol Tablets?
A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.
Q: Is this the generic for Combiflam?
A: Yes, this formulation is the generic equivalent of popular brands like Combiflam or Ibuclin.
Q: Can I take this on an empty stomach?
A: No, it is best taken with food or milk to prevent stomach irritation caused by Ibuprofen.
CLINICAL PHARMACOLOGY & SAFETY INFORMATION
(For Registered Medical Practitioners & Patient Reference)
8. Dosage and Administration
Standard Adult Dose: One tablet every 6 to 8 hours as needed.
Maximum Dose: Do not exceed 3 tablets in 24 hours.
Administration: Take with a full glass of water and food.
9. Side Effects and Precautions
Common Side Effects: Nausea, indigestion, stomach pain, and heartburn.
Contraindications: Active peptic ulcers, severe kidney disease, or allergy to NSAIDs/Aspirin.
Warning: Contains Paracetamol. Do not take with other Paracetamol-containing products to avoid overdose.
10. Storage Instructions
Store below 25°C in a dry place.
Protect from light and moisture.
